What
is Feline Heart Disease-Especially HCM
Unless a heart murmur is the first thing diagnosed in a cat, usually heart disease is diagnosed when the cat is unable to breathe. Many pet owners may not have noticed that for a few days leading up to the moment they noticed the cat's inability to breathe, that the cat may not have been eating well, or may have been lethargic, or looked as if uncomfortable or in pain, or may have had to stop and rest often while walking or running, or may have been breathing rapidly while resting. A cat that is breathing rapidly in distress, will have while sleeping or while resting but not sleeping, rapid chest (or center of the body) heaving movements. It is rare that a cat will cough or will pant with its mouth open while in breathing distress but those should not be dismissed either. Another common sign that pet owners encounter is finding the cat is suddenly having a heart attack or a lame/paralyzed limb. These are caused by a blood clot that has formed in the heart and broken away and traveled through the body. Sometimes, pet owners come home and find that the cat has suddenly died.
In general, there are four types of heart disease seen in cats: HCM-hypertrophic cardiomyopathy, RCM-restrictive cardiomyopathy, DCM-dilated cardiomyopathy, and ARVC-Arrhythmogenic Right Ventricular Cardiomyopathy. While each affects the heart function differently and may have unique symptoms, all four affect the ability of the heart to fully function, can lead to congestion and impaired breathing ability, blood clots, heart attacks, and eventually death.
They share many of
the same symptoms and the medications used to treat the disease.
While HCM and
heart disease leads to death, the progression of the disease varies from
patient to patient depending on the type of heart disease, the age of the cat
at first incident or diagnosis, if the disease was discovered before the cat
became ill of the effects of the disease or whether CHF or
a heart attack or a blood clot occurred first, and the effect of the
medications upon the disease.
Some cats will be
diagnosed while a kitten and may die young while others will live for
years-either with few symptoms or issues or complications or with many
symptoms, issues, and complications. Some
cats will be free of the disease while young but will have the disease appear
around the age of 8-18 and will have a couple of years or a few years left.
The ability of a cat to live with heart disease for any length of time
depends on a pet owner's vigilance, medication therapy, and quality vet care,
as well as the general health of the cat. Controlling congestion, decreasing the likelihood of clots, and keeping the cat free of stress will go a long way in managing the progression of the disease and the effects of the disease on the cat.
"Hypertrophic"
means thickened, where the walls and ventricles of the heart become too thick,
or hypertrophied, making it difficult for the heart to fully function and
contract or pump blood. Other diseases also cause thickening of the left
ventricular wall, including aortic stenosis, hyperthyroidism, and high blood
pressure.
There
are many breeds to which HCM is prevalent: Maine Coon, Sphynx, Ragdoll,
Siberian, etc. But it also includes the regular house cat so basically,
almost any cat is a potential victim of heart disease.
Damage to the Heart
As HCM progresses, the actual structure
of the heart changes and heart function is affected. Thickened muscle walls
become less flexible, and the left ventricle can no longer relax or stretch
efficiently to fill with blood.
These changes can create a heart murmur
because the heart valves don't grow as the heart muscle enlarges. Some
cats will develop a heart murmur that is caused by SAM-systolic anterior motion
in the mitral valve. When a heart murmur is present, it usually can be
heard and that is when the vet will recommend further testing to rule out the
cause of the murmur. Some cats will have heart murmurs that are stress
related but the majority of heart murmurs are heart disease related. Any
known heart murmur must be properly diagnosed so that treatment can begin in
time. Do NOT go by what a vet may say about the "size" of a
murmur, that it is "only" a 1 or 2 or...and can be ignored or that
the size means that heart disease isn't present. The size of the murmur
is not indicative of the extent of heart disease nor a sign of the type of
disease present. And since it can be stress related, may not even indicate the
presence of heart disease. A visit to a cardiologist for xrays and an
echo will be needed.
As the heart muscle walls thicken, as
the heart beats, not all of the body's fluid (blood and water) can be taken
into the valve when the heart valve opens. As the heart valve closes, the
extra or remaining fluid backs up into the lungs or chest cavity, leading to
congestion or congestive heart failure. This is a dangerous time as the
congestion leads to breathing difficulty. Left too long, with the cat in
breathing distress, the lungs will fill with fluid and the cat will die of the
inability to breathe.
As the heart is beating, and after the
valve has opened to receive the body's fluid, the heart valve closes and then
opens again. This process of opening the valve means it is pushing out the
fluid it took in, causing the fluid to go into circulation in the body.
As the heart walls thicken due to disease, there is less ability for the heart
to pump out of the valve the fluid, leading to blood pooling in the valves.
This pooling blood can lead to the creation of clots which can break away from
the interior of the heart and block an artery in either the heart-leading to a
heart attack-or a leg, either of which will be painful and potentially
deadly (clots may settle in other arteries but the heart and legs are the most likely in cats.)
Diagnosis of HCM
If heart disease is suspected, a visit
to a vet cardiologist is necessary. The cardiologist will take xrays to
look at the condition of the lungs and to see if the lungs are congested.
The size of the heart can also be noted on the xrays but only if the
heart is thickened enough as to enlarge it.
The cardiologist will perform an echo or ultrasound which will show how
well the heart is functioning, if there are clots, how thick any valves may be,
and how extensive is the damage to the heart, and which type of heart disease is
present. Blood work known as a CBC/chem panel must be done to see what is the overall health of the body and the effect of heart disease on the body.
While there is a blood
test to test for an HCM gene, the test does not indicate whether HCM or other
heart disease is present at a given moment, only that it is genetically
possible. Nor does a blood test tell of the extent of the damage if
disease is present. An echo is needed even if the gene test is positive. Since the blood test is expensive, unless an owner intends to breed with the cat, the owner-if worried about a cat having heart disease-should see a cardiologist for xrays and an echo.
Treatment Options for Cats with HCM
There are many different types of
medications that can be given to a cat depending on severity of the
disease. (See the Med tab for further information.)
Lasix is a diuretic and is necessary to
rid the body of extra fluid and to control the level of fluid in the body. Will
help prevent or decrease the ability of CHF to form and will aid in the
breathing function.
ACE inhibitors such as enalapril, slow the heart rate and lower blood pressure and keep blood veins from being
constricted.
Beta blockers such as atenolol slow
the heart rate and help lower blood pressure.
Plavix and aspirin
act as blood thinners which decreases the chance of a blood clot forming;
thinner blood lessens the work of the heart.
Spironolactone acts
as a diuretic and helps to preserve much needed potassium which is necessary
for kidney function.
A cat with
heart disease and which is on meds, needs a good overall vitamin made for cats.
Other supplements
that aid in heart health are amino acids (those formulated only for cats), and COQ10. Potassium supplements (cats may take almost any form made for humans but
check the brand or type with your vet) will increase the blood potassium levels
that usually fall due to the much needed lasix. The vet will do a
CBC/chem blood panel from time to time to check the body's function and overall
health as well as the effects of medications on the liver and kidneys. The
results should always be reviewed with
the vet and any levels too high (hyper) or too low (hypo) should be discussed.
Other Types of Heart
Disease
Dilated
cardiomyopathy results in heart chambers that are dilated in size.
It was once a common heart disease in cats and was caused by a lack
of taurine in a cat's diet. Once commercial cat food was made with
taurine, the disease almost disappeared. Now it is rarely seen. If
diagnosed, it is either due to homemade diets that lack taurine or could still
be possibly genetic. Cats with dilated cardiomyopathy that is due to
taurine deficiency generally respond well to supplementation with taurine but
any damage that was caused may not be reversible. Drugs used to treat
dilated cardiomyopathy are similar to those used in hypertrophic
cardiomyopathy.
In restrictive cardiomyopathy,
the heart muscle in the ventricle of the cat contains a large amount of
fibrosis or scarred tissue. This results in the ventricles being stiffer
than normal, making it more difficult for them to contract normally. This leads
to a failure of the heart's ability to pump blood effectively. Symptoms
of restrictive cardiomyopathy in cats are similar to those seen with other
cardiomyopathies. But usually, RCM cats get congestion in the chest
cavity as well as the lungs and must have fluid withdrawn from the body.
They may be given many of the same drugs as with HCM.
Arrhythmogenic right
ventricular cardiomyopathy (ARVC) is a form of
cardiomyopathy that affects the right side of the heart. Symptoms are those of
right-sided heart failure, including ascites (fluid in the abdominal cavity)
and swelling in the legs. An arrhythmia (abnormal heart rate or rhythm)
may also be present.
Websites with Information Regarding HCM
Websites with Information Regarding HCM
Harpsie-a person's website about their HCM cat experience that discusses felinediseases with links to further information.
A vet's website regarding HCM in cats.
A link to Long Beach California vet hospital's discussion re: HCM. Useful terms, descriptions, and illustrations.
An older site from around 2007 with basic information and drawings and details.
A pamphlet with HCM information.
PetMD offers HCM information as well as general cat health information.
Cornell University College of Veterinary Medicine
University of Minnesota has a page with definitions and 3D imaging about the heart
Knowing and using medical terms will help you better discuss issues with the vet:
Medical terms to know.
Know, understand, and how to use medical measuring/dosing terms such as "q", "TID", etc.
This site offers information about understanding blood chemistry values.
A good source for definitions and terms relating to the heart and heart disease
A pet owner must be aware of many things affecting a cat that has heart disease:
Different types of congestion may occur in cats with heart disease:
Pulmonary
edema-fluid
buildup in the lungs. It leads to impaired gas exchange and may
cause respiratory failure. Treatment is focused
on three aspects: improving respiratory function, treating the underlying
cause, and avoiding damage to the lung. Pulmonary edema, especially in the
acute setting, can lead to respiratory failure, cardiac arrest due
to hypoxia and
death. Low oxygen saturation and disturbed arterial blood gas readings support
the proposed diagnosis. Echos may strengthen the diagnosis by
demonstrating impaired left ventricular function, high central venous pressures and high pulmonary artery pressures. The causes of
pulmonary edema can be divided into cardiogenic and non-cardiogenic. By
convention cardiogenic refers to left ventricular causes. Non-cardiogenic
are varied and can include hypertensive due to a combination of increased
pressures in the right ventricle and pulmonary circulation and also
increased systemic
vascular resistance and
left ventricle contractility increasing
the hydrostatic pressure within the
pulmonary capillaries leading to extravasation of
fluid and edema. Patient is given oxygen and
diuretics and other heart meds to manage any heart conditions and to stabilize
the heart.
Pleural effusion-fluid buildup around
the lungs in the pleural cavity, easier to aspirate-withdraw with a needle.
This procedure is done every few weeks. The cat will feel better for 2-3 weeks
before beginning to feel poorly again, at which point, the cat needs to see the
vet again. Symptoms might include coughing, difficult
breathing, increased rate of breathing, cat cannot sit comfortably, and may or
may not have open mouth breathing. Might also have a lack of energy and a
lack of appetite.
No comments:
Post a Comment